Na***nal Institutes of Health (.gov) : Genome-wide Studies of CCCTC-binding Factor (CTCF) ...
by BK Lee · 2012 · Cited by 122 — In somatic cells, the Igf2/H19 ICR shows differential DNA methylation according to parental ... 281, 30573–30580 [PubMed] [Google Scholar].
Gu*** to the Human Genome : Insulators: many functions, many mechanisms
by AG West · 2002 · Cited by 824 — CTCF Regulates Allelic Expression of Igf2 by Orchestrating a ... STRENGTH AND INSULATOR NUCLEOSOME DEPLETION J Biol Chem October 13, 2006 281: 30573-30580.
Ce*** : Article
by SH Song · 2007 · Cited by 246 — the Igf2/H19 imprinted locus (Lopes et al., 2003), and the androgen receptor locus (Wang et al. ... 281, 30573–30580. 822 Molecular Cell 28, ...
Th***ournal of Biological Chemistry : Genome-wide Studies of CCCTC-binding Factor (CTCF) ...
by BK Lee · 2012 · Cited by 122 — the imprinting control region (ICR) of the mouse Igf2/H19 gene (. 18. Bell C; Felsenfeld G. ... 2006; 281: 30573-30580. View in Article.
PL*** : Border of the Murine Scl Transcriptional Domain
by GA Follows · 2012 · Cited by 8 — ... enhancer-blocking activity have been identified like Igf2/H19 ICM which contains four CTCF binding sites [36], [37]. ... J Biol Chem 281: 30573–30580.
PL*** : Mapping and Functional Characterisation of a CTCF
by GA Follows · 2012 · Cited by 8 — blocking activity have been identified like Igf2/H19 ICM which contains four CTCF binding sites [36,37]. ... J Biol Chem 281: 30573–30580.
Ox***d University Press : Sertoli-Sertoli and Sertoli-Germ Cell Interactions and Their ...
by DD Mruk · 2004 · Cited by 1023 — d. General discussion on the regulation of the blood-testis barrier based on recent in vitro and in vivo studies. ; IFN-γ, Perturbed function ...
Un***rsity of Western Ontario : Regulation of Imprinted Genes in the brain by the ATRX ...
by KD Kernohan · 2013 — across H19/Igf2. A role for ATRX in cis at several imprinted genes is supported by its ability ... biological chemistry 281:30573-30580.
Ad***ne : pSpCas9(BB)-2A-GFP (PX458) Citations
2015 Dec 18;290(51):30573-86. doi: 10.1074/jbc. ... Disruption of the ZBED6 binding site in intron 3 of IGF2 by CRISPR/Cas9 leads to enhanced muscle ...
Pe***e also ask : How do DNA insulators work?
Insulators are DNA sequence elements that can serve in some cases as barriers to protect a gene against the encroachment of adjacent inactive condensed chromatin. Some insulators also can act as blocking elements to protect against the activating influence of distal enhancers associated with other genes.
Pe***e also ask : What is insulator in gene expression?
Insulators prevent enhancer-promoter interactions between certain elements that are close (at endogenous locations or brought into proximity through chromosomal rearrangements). Moreover, TADs can help regulatory elements and promoters ove otherwise prohibitory linear distances between them to enable regulation.
Pe***e also ask : What is the function of the insulator element?
Insulator elements can be classified as enhancer-blocking or barrier insulators depending on whether they interfere with enhancer-promoter interactions or act as barriers against the spreading of heterochromatin.
Pe***e also ask : What are insulators in transcription?
Insulators are DNA sequence elements that prevent inappropriate interactions between adjacent chromatin domains. One type of insulator establishes domains that separate enhancers and promoters to block their interaction, whereas a second type creates a barrier against the spread of heterochromatin.
Eu***ean Bioinformatics Institute : Genome-wide analyses of transcriptional regulation across ...
alpha gene(114), as well as the Igh locus(115) and the classic Igf2/H19 imprinting control ... J Biol Chem 281, 30573–80. 17, 24.