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cl***caltrials : ORIN1001 in Patients With Advanced Solid Tumors and ...
Brief Summary: This study evaluates the anti-tumor effects of ORIN 1001 in patients with advanced solid tumors or relapsed refractory metastatic breast cancer ( ...
cl***caltrials : Evaluation of Oral ORIN1001 in Subjects With Idiopathic ...
Nov 25, 2020 — This Phase 1b trial is a double-blind, placebo-controlled, multiple ascending dose study to evaluate the safety and tolerability of oral ...
Pu***nary Fibrosis Foundation : ORIN1001 | Pulmonary Fibrosis Foundation
Study Purpose. This Phase 1b trial is a double-blind, placebo-controlled, multiple ascending dose study to evaluate the safety and tolerability of oral ORIN1001 ...
Ba***r College of Medicine : ORIN1001-001: A Dose Escalation Study of Oral ORIN001 ...
Jan 8, 2021 — This study is being done to learn more about the safety and effectiveness of an investigational oral medication called ORIN1001 for people ...
Pe***e also ask : What is ORIN1001?
Background: ORIN1001 is a first-in-class small molecule targeting a novel enzyme with a unique mode of inhibition that selectively blocks the Inositol Requiring Enzyme 1\u03b1 (IRE1) RNAse and blocks X-Box Binding Protein 1 (XBP1) activation in the endoplasmic reticulum.
Me***emExpress : breast cancer | MedChemExpress Life Science Reagents
FTI-2148 is a RAS C-terminal mimetic dual farnesyl transferase (FT-1) and ... Orin1001. IRE1 · Cancer. MKC8866, a salicylaldehyde analog, is a potent, ...
Un***rsity of Miami Health System : ORIN1001 in Patients With Advanced Solid Tumors and ...
ORIN1001 in Patients With Advanced Solid Tumors and Relapsed Refractory Metastatic Breast Cancer · Clinical Trial Summary · Phase. Phase 1/Phase 2 · Funding Agency ...
Un***rsity of California, Irvine : ORIN1001 in Patients With Advanced Solid Tumors and ...
Jan 13, 2023 — This study evaluates the anti-tumor effects of ORIN 1001 in patients with advanced solid tumors or relapsed refractory metastatic breast ...
Sc***d : Clinical Trials at Sarah Cannon | PDF
392 NCT02543Study of a Novel BET ResultsAcute MyeDrug: FT-1 Maximum To ... Adult) InterventioAllocation ORIN1001- 25-May-19 18 Years and
La***l Delta : ORIN1001 / Fosun Pharma
Combination therapy • Monotherapy • Trial date • Trial primary date • Cervical Cancer • Esophageal Squamous Cell Carcinoma • Hormone ...
Ce***rWatch : ORIN1001 in Patients With Advanced Solid Tumors and ...
This study evaluates the anti-tumor effects of ORIN 1001 in patients with advanced solid tumors or relapsed refractory metastatic breast cancer (patients ...