Na***nal Institutes of Health (.gov) : RBM10: Harmful or helpful‐many factors to consider - PMC
by JJ Loiselle · 2018 · Cited by 26 — Zhao J, Sun Y, Huang Y, et al. Functional analysis reveals that RBM10 mutations contribute to lung adenocarcinoma pathogenesis by deregulating splicing.
Na***nal Institutes of Health (.gov) : Functional analysis reveals that RBM10 mutations ...
by J Zhao · 2017 · Cited by 66 — RBM10 is an RNA splicing regulator that is frequently mutated in lung adenocarcinoma (LUAD) and has recently been proposed to be a cancer gene.
Pe***e also ask : What is the function of RBM10?
RBM10 inhibits the Notch signaling pathway by alternative splicing of Numb gene and affects cell proliferation (16). Numb is a tumor suppressor, and the Notch pathway is the key proliferation pathway affected in breast cancer (37).
Pe***e also ask : What are the domains of RBM10?
RBM10 has two RNA-binding domains in the N-terminal region: the RRM1-C4 ZnF di-domain and RRM2 domain. RBM10 isoforms 1 \u2013 4 are determined by the inclusion or exclusion of the region encoded by exon 4 (box at residues 68\u2013144) and of a Val residue at 354 (open triangle) (see also Fig. 3).
Na***e Journal : Functional analysis reveals that RBM10 mutations ...
by J Zhao · 2017 · Cited by 66 — RBM10 is an RNA splicing regulator that is frequently mutated in lung adenocarcinoma (LUAD) and has recently been proposed to be a cancer ...
Sc***ceDirect : RBM10: Structure, functions, and associated diseases
by A Inoue · 2021 · Cited by 21 — RBM10 is a nuclear RNA-binding protein (RBP) that regulates the ... There is a cross-regulation between RBM5 and RBM10 (Sun et al., 2017, ...
Sc***ceDirect : RNA binding motif protein 10 suppresses lung cancer ...
by S Zhang · 2020 · Cited by 23 — The gene encoding splicing factor RNA binding motif protein 10 (RBM10) has been found frequently mutated in various types of cancer, particularly lung ...
Fr***iers : RBM10 Regulates Tumor Apoptosis, Proliferation, and ...
by Y Cao · 2021 · Cited by 15 — The RNA-binding motif protein 10 (RBM10) is involved in alternative splicing and modifies mRNA post-transcriptionally.
Fr***iers : RBM10 Deficiency Is Associated With Increased Immune ...
by B Liu · 2021 · Cited by 5 — Conclusion: Our study demonstrates that RBM10 deficient LUADs show higher HLA expression and immune cell infiltration, and some immune ...
Ox***d Academic : Autoregulation of RBM10 and cross ... - Oxford Academic
by Y Sun · 2017 · Cited by 42 — Mutations in the spliceosomal RNA binding protein RBM10 cause TARP syndrome and are frequently observed in lung adenocarcinoma ... Yue Sun,.
Sp***idos Publications : Functional role of RBM10 in lung adenocarcinoma ...
by X Sun · 2019 · Cited by 30 — Elevated epidermal growth factor receptor (EGFR)-mediated proliferative signaling is an independent factor leading to tumor progression (6), ...
At*** Antibodies : Rabbit Polyclonal Anti-RBM10 Antibody - Buy for research
Rabbit Polyclonal Anti-RBM10 Antibody against Human RNA binding motif protein 10. Antibody validation: Validated for Immunofluorescence, ...