Re***ed searches : Related searches
slc26a4,slc26a6,slc26a2
Na***nal Institutes of Health (.gov) : SLC26A3 solute carrier family 26 member 3 [ (human)]
Jun 11, 2023 — SLC26A3 (DRA) is stimulated in a synergistic, intracellular Ca[2+]-dependent manner by cAMP and ATP in intestinal epithelial cells.
Pe***e also ask : What is down regulated in adenoma?
The down-regulated in adenoma (DRA) gene was originally identified as a gene that was down-regulated in colon tumors. It encodes a protein with anion transporter function that is expressed predominantly in the mucosa of the lower gastrointestinal tract.
Pe***e also ask : What is congenital chloride diarrhea?
Congenital chloride losing diarrhea (CCLD) is a rare type of chronic watery diarrhea due to mutations in SLC26A3 gene leading to defective chloride–bicarbonate exchanges with the resultant loss of chloride and retention of bicarbonate.
Pe***e also ask : What is the function of SLC26A3 gene?
Slc26a3 contributes to sulfate secretion via DIDS-senstive bicarbonate-sulfate exchange in addition to being the principal DIDS-resistant chloride-bicarbonate exchanger.
Ge***ards : SLC26A3 Gene - Solute Carrier Family 26 Member 3
May 22, 2023 — SLC26A3 (Solute Carrier Family 26 Member 3) is a Protein Coding gene. Diseases associated with SLC26A3 include Diarrhea 1, ...
Wi***edia : Chloride anion exchanger
Chloride anion exchanger, also known as down-regulated in adenoma (protein DRA), is a protein that in humans is encoded by the SLC26A3 gene.
On***e Mendelian Inheritance in Man : SOLUTE CARRIER FAMILY 26, MEMBER 3; SLC26A3 - ...
SLC26A3 functions as a chloride/bicarbonate exchanger and is highly expressed in gastrointestinal, pancreatic, and renal tissues (summary by El Khouri et ...
Sc***ceDirect : SLC26A3 - an overview | ScienceDirect Topics
SLC26A3 (DRA) expressed primarily in normal colon and the putative anion transporter (SLC26A6, PAT1) expressed predominantly in the small intestine, ...
Ga***oenterology : A Novel Role of SLC26A3 in the Maintenance of Intestinal ...
by A Kumar · 2021 · Cited by 40 — The down-regulated in adenoma (DRA) protein, encoded by SLC26A3, a key intestinal chloride anion exchanger, has recently been identified as ...
Bi***d Central : Functional characterization of SLC26A3 c.392C>G (p ...
by N Zhang · 2019 · Cited by 3 — SLC26A3 is a Cl−/HCO3− exchanger that contributes to intestinal fluid absorption and enterocyte acid/base balance [7, 8], which has been ...
Ox***d University Press : Slc26a3 (DRA) in the Gut: Expression, Function, Regulation ...
by Q Yu · 2021 · Cited by 18 — Slc26a3 is the first member from the SLC26 gene family to be cloned. In 1993, Schweinfest et al discovered a gene named as downregulated in ...
Th***uman Protein Atlas : SLC26A3 protein expression summary
The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions.